| 1. |  | USX Tower | 256,3 |
841 |
1970 | 355 | 87 |
| 2. |  | Mellon Bank Center | 221,0 |
725 |
1983 | 169 | 39 |
| 3. |  | One PPG Place | 193,5 |
635 |
1984 | 232 | 29 |
| 4. |  | Fifth Avenue Place | 187,8 |
616 |
1988 | 108 | 22 |
| 5. |  | One Oxford Centre | 187,5 |
615 |
1983 | 103 | 23 |
| 6. |  | Gulf Building | 177,4 |
582 |
1932 | 115 | 25 |
| 7. |  | Cathedral of Learning | 163,1 |
535 |
1936 | 151 | 22 |
| 8. |  | Three Mellon Center | 158,5 |
520 |
1951 | 40 | 46 |
| 9. |  | One Oliver Plaza | 155,8 |
511 |
1968 | 45 | 30 |
| 10. |  | Grant Building | 147,8 |
485 |
1927 | 77 | 32 |
| 11. |  | Koppers Building | 144,8 |
475 |
1929 | 114 | 20 |
| 12. |  | Two PNC Plaza | 135,6 |
445 |
1976 | 150 | 20 |
| 13. |  | Dominion Tower | 131,1 |
430 |
1987 | 76 | 14 |
| 14. | | Regional Enterprise Tower | 125,0 |
410 |
1953 | 0 | 0 |
| 15. |  | Federated Tower | 109,1 |
358 |
1982 | 79 | 13 |
| 16. |  | Westinghouse Tower | 108,2 |
355 |
1970 | 50 | 42 |
| 17. | | Oliver Building | 105,8 |
347 |
1910 | 0 | 0 |
| 18. |  | Three Gateway Center | 104,9 |
344 |
1952 | 61 | 21 |
| 19. |  | Frick Building | 100,6 |
330 |
1902 | 73 | 16 |
| 20. |  | Allegheny County Courthouse | 76,2 |
250 |
1888 | 69 | 15 |
| 21. |  | Litchfield Towers | |
|
1966 | 51 | 33 |
| 22. |  | 601 Grant Street | |
|
1958 | 37 | 26 |
| 23. |  | Midtown Towers | |
|
1907 | 75 | 16 |
| 24. |  | Penn Station | |
|
1903 | 110 | 23 |