| 1. |  | Comcast Center | 296,6 |
973 |
2008 | 416 | 85 |
| 2. |  | One Liberty Place | 288,0 |
945 |
1987 | 259 | 40 |
| 3. |  | Two Liberty Place | 258,5 |
848 |
1989 | 216 | 33 |
| 4. |  | Mellon Bank Center | 241,4 |
792 |
1990 | 190 | 30 |
| 5. |  | Bell Atlantic Tower | 225,2 |
739 |
1991 | 112 | 27 |
| 6. |  | G. Fred DiBona, Jr. Building | 213,4 |
700 |
1990 | 98 | 24 |
| 7. |  | Commerce Square I & II | 174,3 |
572 |
1987 | 78 | 27 |
| 8. |  | Philadelphia City Hall | 167,0 |
548 |
1901 | 226 | 55 |
| 9. |  | 1818 Market Street | 152,4 |
500 |
1974 | 55 | 34 |
| 10. |  | The St. James | 151,8 |
498 |
2004 | 55 | 16 |
| 11. |  | PSFS Building | 150,0 |
492 |
1932 | 96 | 19 |
| 12. |  | Centre Square I & II | 149,4 |
490 |
1973 | 63 | 18 |
| 13. |  | The Murano | 144,8 |
475 |
2008 | 96 | 22 |
| 14. |  | PNB Building | 143,9 |
472 |
1930 | 70 | 12 |
| 15. |  | Two Logan Square | 132,6 |
435 |
1987 | 69 | 12 |
| 16. |  | Cira Centre | 132,3 |
434 |
2005 | 130 | 21 |
| 17. |  | Wachovia Building | 123,4 |
405 |
1927 | 63 | 10 |
| 18. |  | PECO Building | 117,0 |
384 |
1970 | 52 | 26 |
| 19. |  | The Drake | 114,3 |
375 |
1929 | 117 | 22 |
| 20. |  | One East Penn Square Building | 106,1 |
348 |
1930 | 53 | 6 |
| 21. |  | Inquirer Building | 103,6 |
340 |
1924 | 70 | 9 |
| 22. |  | Society Hill Towers | 89,0 |
292 |
1964 | 56 | 37 |
| 23. |  | Cathedral of SS. Peter and Paul | 49,4 |
162 |
1864 | 77 | 14 |
| 24. |  | Memorial Hall | 45,7 |
150 |
1876 | 55 | 7 |
| 25. |  | 30th street station | 35,4 |
116 |
1934 | 98 | 15 |